Abstract
Following our previous study of the therapy of onychomycosis by non-thermal plasma (NTP) and nail hygiene and to obtain some prerequisite data of dermatophytes sensitivity, the dynamics of those inactivation by NTP plasma was monitored for various strains of Trichophyton iterdigitale, Trichophyton benhamiae, Trichophyton rubrum, and Microsporum canis. Three strains of each species on agar plates were exposed with plasma produced by a DC corona discharge in the point-to-ring arrangement in various time intervals. Although all strains were sufficiently sensitive to plasma action, significant differences were observed in their sensitivity and inactivation dynamics. These differences did not correlate with the species classification of individual strains, but could be assigned to four arbitrarily created types of strain response to NTP according to their sensitivity. These results indicate that the sensitivity to plasma is not an inherent property of the fungal species, but varies from strain to strain.
Highlights
Micromycetes, filamentous microscopic fungi or molds, can cause food degradation.They are important in medicine as causes of general infections, mycotoxicoses and allergies, as well as local infections
To evaluate the growth of micromycetes on the dish, the percentage of the area on the exposed part of the dish overgrown with micromycete was chosen as a criterion
Designing the fungal species should be characterized by Designingthis thiswork, work,we weassumed assumedthat that the fungal species should be characterized its to plasma exposure
Summary
Micromycetes, filamentous microscopic fungi or molds, can cause food degradation They are important in medicine as causes of general infections (invasive mycoses), mycotoxicoses and allergies, as well as local infections (superficial and mucosal mycoses, dermatomycoses). This group of dermatophytes includes mainly the genera Trichophyton and Microsporum, containing approximately ten species of parasitic fungi. Topically applied preparations based on imidazoles, allylamines, pyridines, or morpholines are recommended. The relatively low efficacy of the classical therapy has motivated efforts to apply new physical therapy methods
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