Abstract
THE anticurare action of ‘Tensilon’ (3-hydroxy-N-dimethylethylanilinium bromide) was considered by Randall1,2 not to depend upon cholinesterase inhibition. Hobbiger3 and Hall and Parkes4 showed, however, that ‘Tensilon’ does not reverse neuromuscular block after treatment of the preparation with tetraethyl pyrophosphate, implying the necessity of active cholinesterase for the effect.
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