Abstract
Background: Mandur Bhasma is a herbo-mineral compound. It is prepared by Putapaka method. It is described as Raktasanjanan. In the current study, Mandur Bhasma was prepared with a standardized method w.s.r to Rasatarangini and an experimental study was done to observe the Angiogenic property of Mandur Bhasma. The current study will analyze angiogenic potential of Mandur Bhasma using chick CAM model. This research is intended to study the possible role of Mandur Bhasma on angiogenesis and establishing properties of Mandur Bhasma as an angiogenic by newer means. The experimental study inside the egg shell will be carried out on a membrane known as “chorioallantoic membrane”.
 Objectives:
 
 To Prepare Mandur Bhasma
 Physicochemical and Analytical study of Mandur Bhasma
 To verify the angiogenic potential of Mandur bhasma using the chicken chorioallantoic membrane (CAM) model.
 To compare Angeogenic potential of Mandur bhasma with standard drug progesterone
 
 Methodology: Relevant classical literature regarding Mandur will be reviewed and the data will be collected. Mandur Shodhan with Gomutra and Mandur Maran with Triphala decoction will be done.
 Analytical Study like Organoleptic Test for Rasa, Gandha, Varna, Sparsha, Physicochemical Tests and other analytical test like ICP-AES /ICPMS, XRD structure of Bhasma, EDAX-NANO Particle Size will be done.
 Expected Results: Changes will be observed in objective outcomes. 
 Conclusion: Conclusion will be drawn by suitably analyzing data.
Highlights
1.1 Background/RationaleAyurveda mentions the use of raw materials from natural sources for preparations of different Aushadhi Kalpanas which are useful as preventive measures as well in the ailments
Experimental study includes a chorioallantoic membrane (CAM) Model [10-15] and its angiogenesis effect is explained in review of literature
Null Hypothesis: There is no significant difference between Mandur Bhasma and progesterone in angiogenic potential
Summary
Ayurveda mentions the use of raw materials from natural sources for preparations of different Aushadhi Kalpanas which are useful as preventive measures as well in the ailments. Experimental study includes a CAM Model [10-15] and its angiogenesis effect is explained in review of literature. The review of literature has been helpful to understand in detailed information of the above concepts, the properties and characteristics of the raw materials. Mandur Bhasma was prepared with a standardized method w.s.r to Rasatarangini and an experimental study was done to observe the Angiogenic property of Mandur Bhasma. The current study will analyze angiogenic potential of Mandur Bhasma using chick CAM model.
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