In-vivo reflectance confocal microscopy in patients with chromoblastomycosis

Abstract

In-vivo reflectance confocal microscopy (RCM) is a non-invasive technique that provides real-time images of the skin structure in grey scale, at a resolution similar to histopathology, in planes parallel to the skin surface to the depth of the superficial dermis (Gonzalez, 2012). Highly reflective skin components, such as melanin, act as an endogenous source of contrast and appear bright white in RCM images. Chromoblastomycosis is an infectious disease characterized by the occurrence of verrucous plaques on the limbs.