Abstract

Ferrimagnetic micro particles of Fe 3O 4 were used to investigate the intracellular viscoelastic properties of alveolar macrophages in vivo. After primary strong field magnetization and complete relaxation the lung was remagnetized by a weak magnetic field. In this case the balance between magnetic torque and hydrodynamic retarding torque allows to model remagnetization. The deviations between measurements and theory make it necessary to estimate a non-Newtonian intracellular viscosity. The measurements were analysed according to the shear rate dependence of intracellular viscosity, giving a viscosity of 130 Pa·s a shear rate of 0.01 s −1, while it increases to above 10 3 Pa·s for shear rates below 0.001 s −1.

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