Abstract

This study aimed to evaluate the immunological potential of Plantago lanceolata through determination of (total and absolute count of white blood cell, total count of red blood cell and total count of hemoglobin). The results indicated the ability of plant extract to modulate toxic effect of methotrexate on albino mice by enhancing immunity through all tested parameters All this effect due to the presence of chemical active constituents of plant especially (flavonoid and alkaloids).

Highlights

  • The widespread use of Complementary and Alternative Medicine (CAM) is a major importance to today's health care consumers, practitioners, researchers, and policy makers

  • This study aimed to evaluate the immunological potential of Plantago lanceolata through determination of

  • An increase in the white blood cell (WBC) count was observed in mice administered lantago lanceolata, the measurement of WBC was 11500 cell and this can suggests that Plantago lanceolata extract contains terpenes

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Summary

Introduction

The widespread use of Complementary and Alternative Medicine (CAM) is a major importance to today's health care consumers, practitioners, researchers, and policy makers. History of medicine and plants dates back to remote past when herbal treatment was the only answer to all kind of ailments [3]. Herbal medicine is a traditional or folk medicine practice based on the use of plants’ seeds, berries, roots, leaves, barks, flowers and plant extracts for medicinal purposes [5], where natural products derived from plants used for the treatment of diseases and show the relationship between the man and his environment [6]. [9] Plantago lanceolata historical underpinnings, Plantago gets from the Latin word planta, signifying “young plant” or “sole of the foot”. Lanceolata gets from the Latin expression for a lance or spear, and is generally used to demonstrate a species with narrow leaves that taper to a point at one end [10,11]

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