In vivo Comparison of Volume of Interest Determination on Maxillary Bone Regeneration in Orthodontic Treatment: Cone-Beam Computed Tomography Versus Micro-Computed Tomography

Abstract

Orthodontic treatment can result in relapse, side effects associated with Orthodontic Tooth Movement (OTM) are root resorption, bone loss, and gingival inflammation which impairs long-term stability during orthodontic treatment. OTM creates a gap causing relapse after orthodontic treatment. Regenerate bone to prevent relapse after orthodontic treatment. Volume of interest (VOI) measurement by (3 Dimension) 3D imaging Cone-beam computed tomography (CBCT) or Micro-computed tomography (Micro-CT) in vivo. In vivo tests were carried out on 6 Wistar rats aged 5 months and performed 10gf maxillary Molar 1 (M1) withdrawal with 0.010 inch Nickel-Titanium (NiTi) and 8 mm close coil spring, maxillary separation was carried out by CBCT and Micro-CT tests. The tensile force of the orthodontic appliance in the compressed and tense area is a characteristic of OTM causing changes in remodeling. Alveolar bone displacement can occur when tooth roots move through the alveolar cortical bone occurring during OTM. Measurements on samples from CBCT and Micro-CT to investigate the accuracy and reproducibility of landmarks. CBCT resolution 0.0131 µm / pixel and Micro-CT 5.7 µm/pixel, Micro-CT can determine VOI boundaries. Comparison of VOI from CBCT and Micro-CT showed VOI CBCT 9.99% and VOI Micro-CT 22.22%. 3D Micro-CT visualization is more detailed than CBCT, so VOI can be determined easily and more accurately. Detailed, clear, and accurate 3D Micro-CT visualization in the determination of VOI versus CBCT.