Abstract
The genus Cistus (Cistaceae) is one of the characteristic genera of the Mediterranean region, colonizing degraded areas [1]. In Turkish folk medicine, various parts of Cistus laurifolius L. are used to treat peptic ulcer and various types of pains, i.e., rheumatic, back pain, etc. It has been used for the treatment of stomach ache and gastric ulcer in the folk medicine since the time of Dioscorides, i.e., for at least 2000 years in Anatolia. The tea prepared from the leaves is used to decrease symptoms of diabetes hypoglycemic [2,3]. In the present study, the hypoglycemic and antihyperglycemic effects of water and ethanol extracts of C. laurifolius were evaluated by using in vivo methods in normal, glucose loaded hyperglycemic and streptozocin-induced diabetic rats. Diabetes was induced by intraperitoneal injection of streptozocin at the dose of 55mg/kg. Blood glucose levels of animals were measured by the glucose oxidase method. Tolbutamide (100mg/kg) was used as reference drug. All data were compared to control group.
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