Abstract
GL-T, a fraction of extract from fruiting bodies of a fungus, Ganoderma lucidum (Reishi, Ling-Zhi in China) was found to induce protective activity against Candida albicans infection in mice. Of the treatment schedules tested, intraperitoneal administration and premedication were most effective. GL-T stimulated macrophage functions such as phagocytosis and also increased delayed type hypersensitivity and antibody formation in mice. Production of interferons (IFNs) by GL-T was also confirmed, but TNF production was not detectable. The in vivo increased protective activity was abolished by treatment with carrageenan. Possible effectors which may be important in defending against the infection of C. albicans were discussed.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.