Abstract
Intraventricular injection of bromoacetylcholine to rats did not lower brain acetylcholine levels, nor did it inhibit choline acetyltransferase activity. In vitro experiments indicated that bromoacetylcholine can penetrate intact neuronal tissue and inhibit choline acetyltransferase, but that in vivo it is most likely hydrolyzed by cholinesterase before it can exert any inhibitory action. For this reason bromoacetylcholine is unsuitable for in vivo inhibition of choline acetyltransferase.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Published version (
Free)
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
