In vivo analysis of ciliary muscle in myopic Chinese young adults using ArcScan Insight® 100.

Abstract

To analyse the morphological characteristics of the ciliary muscle (CM) and to explore its relationship with different ocular biometric parameters in myopic young Chinese adults. This observational, cross-sectional study included 50 right eyes from 50myopic adults. The CM area (CMA), CM thickness (CMT) and CM length (CML) were measured using the ArcScan Insight® 100. CMT was determined at three points: 1.0mm (CMT-1), 2.0mm (CMT-2) and 3.0mm (CMT-3) posterior to the scleral spur. CML was measured on the scleral (CMLs) and vitreous (CMLv) aspects. The spherical equivalent refraction (SER), axial length (AL) and subfoveal choroidal thickness (SFCT) were examined to determine their associations with CM parameters (CMA, CML and CMT). The mean SER and AL were -4.39±2.29 D and 25.61±1.15mm, respectively. Compared with the nasal CMA, CML and CMT (CMT-1, CMT-2 and CMT-3) findings, the temporal CM parameters (CMA, CMLs, CMLv, CMT-1, CMT-2 and CMT-3) were found to be significantly thicker (all p<0.001, except CMLv and CMT-1; p<0.01). The nasal CMA was associated with the average corneal curvature (r=0.30, p=0.03) and SER (r=-0.30, p=0.04). Nasal and temporal CMT-2 were negatively correlated with SER (r=-0.33 and -0.32, respectively, both p<0.05). There was no correlation between CM parameters (except nasal CMLs, r=0.31, p=0.03) and SFCT, or between CM parameters and either the AL or anterior chamber depth (all p>0.05). These results suggest that there is temporal versus nasal asymmetry of the CM. CMA, CMT or CML did not vary with axial growth of the eye. The CM is not simply stretched as the eye elongates in myopic young adults.