In vitro UV absorption properties and radical scavenging capacity of Morella parvifolia (Benth.) Parra-Os. extracts

Miguel Angel Puertas-Mejía,Juan Camilo Mejía-Giraldo,María Isabel Gutierrez-Villegas,Benjamín Rojano,Robert Winkler

doi:10.1590/s2175-97902018000317498

Abstract

The goal of this research was to identify major compounds of the aerial parts of M. parvifolia (Benth.) Parra-Os., that could enhance its possible application as additive in dermocosmetic products, as well as evaluate the antioxidant properties. The extracts agreed with the broad-spectrum UVB/UVA absorption detected and could act as broad-spectrum sunscreens, covering the UVA and UVB range. Methanolic extracts showed an important antiradical capacity (0.46 and 0.47 g/µmol DPPH), TPC (37.58 and 51.41mg GAE/g DS) and TAC (1.12 and 3.31 mg C3GE/g DS) in fruits and leaves, respectively. M. parvifolia could be considered as a prospective source of natural UV-radiation absorbers with antioxidant capacity. Although the results have clearly demonstrated the potential photoprotection capacity, more studies are needed to enhance its application as an additive in pharmaceutical and medicinal formulations.

Highlights

Natural bioactive compounds isolated from plants may act as potential antioxidant, antimutagenic, antiinflammatory and anticarcinogenic agents to reduce the UV generated ROS-mediated photodamage, immunesuppression and skin cancer in patients (Katiyar et al, 1999; 2000; Stahl et al, 2000; Zhou et al, 2009b; Morales et al, 2011)
The aim of this study was to evaluate the phytochemistry and biological activities of M. parvifolia grown in the Andean Mountains of Antioquia-Colombia, with regard to their in vitro UV-radiation absorption capacity, main phenolic compounds and antioxidant capacity, in order to propose it as non-conventional source of skin-care additives
The highest concentration of Total polyphenol content (TPC) was found in leaf extracts

Summary

Introduction

Natural bioactive compounds isolated from plants may act as potential antioxidant, antimutagenic, antiinflammatory and anticarcinogenic agents to reduce the UV generated ROS-mediated photodamage, immunesuppression and skin cancer in patients (Katiyar et al, 1999; 2000; Stahl et al, 2000; Zhou et al, 2009b; Morales et al, 2011). Morella parvifolia (Benth.) Parra-Os., a shrub that belongs to the Myricaceae family and can be found in Colombia, Venezuela, Ecuador and Perú between 1300 to 3800 meters above sea level, is exposed to adverse environmental conditions such as fluctuations of rainfall and temperature, high humidity, low temperature and high UV radiation (Parra, 2003; Gonzales de la Cruz et al, 2014). These exceptional conditions induce the plants to produce

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