Abstract
Ischemic stroke results from a cerebral vessel occlusion by a blood clot. Treatments are intended to restore the cerebral blood flow as soon as possible to avoid major brain damage. [...]
Highlights
Intravenous administration of recombinant tissue plasminogen activator is the only thrombolytic drug approved for treatment of acute ischemic stroke [1]
In vitro and in vivo studies have shown that recombinant tissue plasminogen activator (rtPA) in combination with ultrasound and microbubbles can improve clot lysis [2]
The exact mechanisms involved in this sonothrombolysis process remain unknown
Summary
Conference abstract PNM18 In Vitro Sonothrombolysis of Human Blood Clots: Preliminary Results 1 School of Pharmaceutical Sciences, University of Geneva, University of Lausanne, Geneva, Switzerland 2 Bracco Research S.A, Plan-les-Ouates, Geneva, Switzerland Ischemic stroke results from a cerebral vessel occlusion by a blood clot. Treatments are intended to restore the cerebral blood flow as soon as possible to avoid major brain damage.
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