IN VITRO SIMULATION RESEARCH ON THE HOOP STRESS OF MYOCARDIAL BRIDGE — CORONARY ARTERY

Hao Ding,Lingxi Zhao,Yanjun Zeng,Lanhai Lian,Lixing Sheng,Kun Shang

doi:10.15829/1560-4071-2014-7-eng-51-54

Abstract

An analog device which can simulate myocardium bridge oppresses mural coronary artery is designed. The device can be used to research the dynamic changes of the proximal and distal hoop stresses. Meanwhile, the independent regulation of the hoop stresses is realized. The “myocardial bridge — coronary artery” analog device is built to adjust the external pressure of the simulated coronary artery and the oppression level of the myocardial bridge and to record the changes of the hoop stresses. The In vitro simulation experiment indicate that the anomaly of hoop stress mainly occurs in the proximal end. As the oppression level increases, the mean proximal hoop stress and the oscillatory value (maximum-minimum) increase obviously. The “myocardial bridge — coronary artery” analog device can provide a method to study the influence of the hoop stress on the mural coronary artery in vitro.

Highlights

The normal coronary artery and its branches are usually located under the epicardium
When a section of the coronary artery covered by the superficial myocardium is located in the myocardium, the coronary artery is called mural coronary artery (MC) and the myocardium is called myocardial bridge (MB)
Sometimes the effect of drug therapy is poor for some MB patients and a part of MB patients even cannot tolerate drug therapy, so percutaneous transluminal coronary angioplasty or stent implantation is usually used for them

Summary

Introduction

The normal coronary artery and its branches are usually located under the epicardium. A patient needs treatment when MC stenosis is over 50%. Sometimes the effect of drug therapy is poor for some MB patients and a part of MB patients even cannot tolerate drug therapy, so percutaneous transluminal coronary angioplasty or stent implantation is usually used for them. Coronary artery stent implantation can correct the abnormal MC hemodynamic, and can make the MC blood flow return to normal. 10% — 50% of the patients may develop stent restenosis after receiving coronary artery stent implantation and even more seriously, the coronary artery rupture may happen in or after the treatment [1,2,3]

Methods

Results

Conclusion