In Vitro Screening of Immunomodulatory Activity of Methanolic Extract of Physalis minima Unripe Fruits

Abstract

At the present plants play a key role in Medicine. Many phyto pharmaceuticals are used to treat different ailments. In the present study, methanolic extract of Physalis minima unripe fruits was screened for immunomodulatory activity using anti-oxidant activity by determining DPPH radical scavenging activity, Hydrogen peroxide scavenging activity, Ferric reducing antioxidant power assay, Immunomodulatory activity by Nitroblue tetrazolium test. The extract showed that the plant extracts have ability to act as free radical scavengers in DPPH radical scavenging activity, reducing ability in Ferric reducing antioxidant power assay, ability to prevent lipid peroxidation in Hydrogen peroxide scavenging activity, ability to stimulate the phagocytic activity in leucocytes in Nitroblue tetrazolium test. The literature survey revealed that these studies were not reported earlier. So, the present study was aimed to reveal the antioxidant and immunomodulatory activity of the plant extract. The study reports concluded that the extract possess immunomodulatory activity.