In Vitro Physical and Biological Evaluations of a 2.4 GHz Electromagnetic Exposure Setup

Abstract

In this paper, a 2.4 GHz electromagnetic radiation system for cells in vitro was designed from the perspective of optimal energy coupling of cell samples. The validity of the design was verified by FDTD simulation, physical test and biological experiment. The electromagnetic parameters of SAR (Specific Absorption Rate) and temperature rise were obtained by FDTD simulation. The validation of temperature simulation was confirmed by comparing the actual measurement data and the simulation data. The SAR relative uniformity between samples was tested by cell biological experiment, in which ROS (Reactive Oxygen Species), a typical and sensitive biological parameter reacting to electromagnetic radiation in cells, of different sample dishes induced by 2.4 GHz electromagnetic radiation with an incident power of 0.5 W was analyzed. We found that the size of cell dish affects the energy coupling intensity, the polarization characteristics of electromagnetic wave determines the distribution pattern of SAR, and the uniformity of sample energy absorption in this radiation system is good.