Abstract
Since there is accumulating evidence for metabolic functions of proopiocortin peptides, we investigated 42 partial sequences for their lipolytic activity in isolated rabbit fat cells. 4 lipolytic active centers can be suggested: in the N-terminal part of proopiocortin (not gamma- and delta-MSH), in the N-terminal region of ACTH (ACTH 4–10), in the β-MSH sequence of β-lipotropin and in the C-terminal region of β-endorphin.
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