Abstract

Objective: A clinical Doppler ultrasound (DUS) machine is an appealing modality to prescribe carotid endarterectomy for prophylaxis against stroke because it is non-invasive and widely available. Doppler ultrasound diagnosis based on peak systolic velocities alone may not have sufficient sensitivity and specificity to diagnose carotid artery disease. Additional information may be obtained from parameters such as turbulence intensity, providing a more accurate view of the hemodynamic factors produced by a stenosed carotid artery. We hypothesize that quantification of turbulence intensity (TI) distal to a severely stenosed carotid bifurcation is possible with conventional DUS, even in the presence of normal physiological cycle-to-cycle cardiac variability.

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