Abstract
Arabinoxylan (AX) is a structural polysaccharide found in wheat, rice and other cereal grains. Diets high in AX-containing fiber may promote gut health in obesity through prebiotic function. Thus, the impact of soluble AX isolated from rice bran fiber on human gut microbiota phylogenetic composition and short-chain fatty acid (SCFA) production patterns from normal-weight and overweight/obese subjects was investigated through in vitro fecal fermentation. Results showed that rice bran arabinoxylan modified the microbiota in fecal samples from both weight classes compared to control, significantly increasing Collinsella, Blautia and Bifidobacterium, and decreasing Sutterella, Bilophila and Parabacteroides. Rice bran AX also significantly increased total and individual SCFA contents (p < 0.05). This study suggests that rice bran AX may beneficially impact gut health in obesity through prebiotic activities.
Highlights
Accepted: 10 June 2021The gut microbiota have received extensive attention in the last two decades because of their important role in host health and gut homeostasis [1]
The gut microbiota are related to many diseases, and the composition of the gut microbiota is known to be affected by diseases such as obesity [6,7], type 2 diabetes mellitus [8,9], cardiovascular diseases [10,11] and colon cancer [12,13]
Our results showed that the level of propionic acid in the AX treatment significantly increased at 24 h compared to control and FOS (p < 0.05)
Summary
Accepted: 10 June 2021The gut microbiota have received extensive attention in the last two decades because of their important role in host health and gut homeostasis [1]. The gut microbiota are related to many diseases, and the composition of the gut microbiota is known to be affected by diseases such as obesity [6,7], type 2 diabetes mellitus [8,9], cardiovascular diseases [10,11] and colon cancer [12,13]. Obesity is a leading public health issue in the US, affecting 42.4% of US adults [15]. It is a proven risk factor for many other diseases, such as type 2 diabetes [16,17], hypertension [18], cardiovascular diseases [19]
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