Abstract
Objective Currently,adsorption materials applied to remove low density lipoprotein (LDL) still remain defects.HB-H-8 resin has not been put in use in removing LDL.This study focused on primary evaluation of adsorption capability of HB-H-8 resin.Methods HB-H-8 resin was used in the adsorption of LDL of patient that was higher than the normal range of blood sample in dynamic test and static test in vitro.Results The time of adsorption saturation was two hours,and the optimum temperature was 37℃.The results of adsorption in vitro showed that the average adsorption rates of LDL and high density lipoprotein (HDL) were 63.2％ and 1.9％,respectively.Conclusion HB-H-8 resin has LDL higher adsorption capability,thus made it to be a potential blood purification material for the removal of LDL. Key words: Low density lipoprotein; High density lipoprotein; Hemoperfusion; Adsorption
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