Abstract
In the context of a clinical trial, we observed a surprisingly high methicillin resistant S. aureus (MRSA) eradication rate of a placebo solution containing a cationic polymeric compound (CPC). The most active compound altering bacterial growth was identified by testing individually all molecules entering the composition of the commercial solution.
Highlights
In the context of a clinical trial, we observed a surprisingly high methicillin resistant S. aureus (MRSA) eradication rate of a placebo solution containing a cationic polymeric compound (CPC)
The most active compound altering bacterial growth was identified by testing individually all molecules entering the composition of the commercial solution
Polyhexanide was rapidly bactericidal for all tested MRSA strains; a rapid decrease of >5 logs in 15 min was generally observed
Summary
In the context of a clinical trial, we observed a surprisingly high methicillin resistant S. aureus (MRSA) eradication rate of a placebo solution containing a cationic polymeric compound (CPC). The most active compound altering bacterial growth was identified by testing individually all molecules entering the composition of the commercial solution
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