Abstract
In Vitro Evaluation of Cytotoxic Effects of Nickel Oxide Nanoparticles on Human Neuroblastoma Cell Line (SH-SY5Y)
Highlights
Background and ObjectivesDespite the many applications of nickel oxide nanoparticles (Nio NPs) in industry and biomedicine, limited studies have been performed in the case of the cytotoxicity of these nanoparticles onnervous system yet
Conclusion: The results of the present study showed that the Nickel oxide nanoparticles do not cause membrane damage in SH-SY5Y cells
While these nanoparticles induce their toxic effects by damaging the mitochondrial membrane, increasing the caspase 3 activity, and activating the apoptotic pathway
Summary
Background and ObjectivesDespite the many applications of nickel oxide nanoparticles (Nio NPs) in industry and biomedicine, limited studies have been performed in the case of the cytotoxicity of these nanoparticles onnervous system yet.
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