Abstract
To test in vitro efficacy of Mebendazole (MBZ), Fenbendazole (FBZ) and Albendazole (ABZ) using egg hatch assay in ancilostomosis and strongyloidiasis in dogs, a number of 62 animals has been studied from Cluj-Napoca, Floresti, Tg. Mures. The ante-therapeutic epidemiology survey conducted revealed that from the total number of dogs taken into the study only 41.93% received annual or biannual anthelmintic treatment. The anthelmintic medication products used were based on benzimidazole derivatives (24.19% of cases). In the case of samples collected form the dogs located in Cluj-Napoca and Floresti, the Mebendazole was most effective taking into account the LC50, which had the lowest value (-0.2352µg/ml respectively -0.1405µg/ml). However the maximum Y parameter was recorded at Fenbendazole (-1538.57 respectively -1754.82). In samples collected from dogs located in Tg. Mures the maximum efficacy was recorded at Fenbendazole with LC50 of -0.1052µg/ml and Y of -1880.42.
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