“In vitro efficacy of antiseptics to control Candida albicans present in the oral mucosa of apparently healthy patients"

Abstract

Candida species are present in the flora of the skin and mucosa of man, and are of common occurrence in the oral cavity of healthy individuals, Candida albicans being the predominant species in the oral microbiota. Therefore, this study was to verify in vitro the effectiveness of oral antiseptics such as chlorhexidine digluconate 0.12%, Cepacol ®, Flogoral ® and Melaleuca 0.2% in the control of Candida albicans. We selected 30 strains of Candida albicans stored in specific culture medium. To the Mueller Hinton Agar - Biobras ® was added sterile paper disks impregnated with the antiseptics studied, and then the samples were incubated at 37 ° C for 24 - 48 hours. Evidence of antifungal activity was the formation of inhibition zone around the paper disk, and evaluated by measuring the halos with a millimeter ruler. According to the results, it is clear that Chlorhexidine was startled on the other oral antiseptics because it has a broad spectrum of activity against various microorganisms. The Cepacol ® also stands out from others because it has a certain efficacy against the some microrganisms. The Flogoral ® and Melaleuca is not observed as effective in the treatment of C. albicans.