Abstract
This experiment was undertaken to determine the in vitro effects of aqueous extracts of Spigelia anthelmia L (a local anthelmintic plant) on experimentally isolated guinea pig ileum, with a view to establishing its likely anthelmintic effect on nematodes. The extract induced concentrationdependent contractile responses similar to that produced by acetylcholine on isolated guinea pig ileum. The contractions produced by the extract were antagonised by atropine but not by mepyramine. It was concluded that the anthelmintic mechanism of action of Spigelia anthelmia is most probably due to paralysis of the worms.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
