Abstract
Using [ 14C]-acetate as a labelled precursor, the effects of fluoride on bone lipid, radioactivity and 14CO 2 production were observed following short-term incubation of rat calvaria, with or without various concentrations of fluoride. While 50 ppm fluoride resulted in lower levels of lipid radioactivity, the differences could have been due to chance alone. A concentration of 100, 200 or 400 ppm fluoride caused a reduction in lipid radio-activity and lowered production of 14CO 2 when compared to control samples.
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