Abstract
BackgroundDuring the last few decades, there has been a growing interest in the search for novel bioactive compounds from marine origins.MethodsThe present study is the first to determine the molecular characterization which it was deposited in the genebank database, to investigate and evaluate the biological properties of sulfated polysaccharide from Cymodocea nodosa (CNSP) seagrass.ResultsThe results revealed that CNSP had high activity in total antioxidant assay (59.03 mg ascorbic acid equivalents/g extract), reducing power (OD = 0.3), DPPH radical scavenging (IC50 = 1.22 mg/ml) and ABTS radical scavenging (IC50 = 1.14 mg/ml). It was also noted to exhibit antimicrobial activity against a wide range of microorganisms, with important inhibition zones. The results revealed that CNSP was able to inhibit the proliferation of Hela cell lines with a dose-dependent manner.ConclusionOverall, the results presented in this study demonstrate that CNSP has several attractive antioxidant, antimicrobial and antiproliferative properties with potential benefits towards health.
Highlights
During the last few decades, there has been a growing interest in the search for novel bioactive compounds from marine origins
In our previous study [9], we indicated the physicochemical, techno-functional and structural characteristics of the sulfated polysaccharide extracted from Cymodocea nodosa (CNSP), which conferred on the nutritional and functional properties very sought after in the food sector
The monomeric composition constituting this polymer was demonstrated by a thin layer chromatography step which revealed spots which correspond to monosaccharides obtained by gas chromatography-mass spectrometry (GC-MS) chromatographic analysis
Summary
During the last few decades, there has been a growing interest in the search for novel bioactive compounds from marine origins. Many marine resources have attracted attention in the search for bioactive compounds, in order to develop new drugs and dietetic foods. Sulfated polysaccharides are natural substances well known for their biological properties. They act as free radical scavengers for the protection of living organisms from oxidative damage [1], antibiotics [2] and as antiproliferative agents [3]. The literature indicates that the marine environment offers a rich source of structurally diverse and bioactive polysaccharides [4]. The search of new nutritional antioxidants from marine plant sources has received an important attention in recent research. The protective effects of antioxidants derive from their capacities to (I) scavenge free radicals
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
