In vitro bacteriological study on film burn wound coverings

Abstract

A novel approach to treating burn wound sepsis is described and an in vitro evaluation of its potential considered. A copolymer semipermeable plastic film incorporating various agents has been shown to exert an antibacterial effect when placed in contact with growing organisms such as those normally found at a burn wound site. Of four agents tested, silver sulphadiazine proved most effective and a quantitative study showed that 10 per cent w/w of this agent in the film could afford effective control of bacterial growth in vitro.