Abstract
BackgroundProbiotics affect both the development and stability of microbiota by altering the colonization of pathogens and thus helps in stimulating the immune system of the individual. The aim of the present study is to assess the effect of probiotics on peri-implantitis microflora, by determining the minimum inhibitory concentration (MIC) of Lactobacillus reuteri, that can be effectively administered as an antimicrobial agent on specific peri-implantitis pathogens. Hence, this study will be helpful in finding the MIC of L. Reuteri that can be effectively administered as an antimicrobial agent on specific peri-implantitis pathogens.MethodsThis experimental research was conducted on patients visiting the periodontology department in M. A. Rangoonwala college of dental sciences and research centre. Sub-gingival plaque samples were collected from peri-implantitis patients to identify various peri-implantitis microorganisms. The identified microorganisms were compared to each other and Chi-Square test was used to calculate statistical significance. The isolated microorganisms were subjected to the effect of probiotic Lactobacillus reuteri in-vitro. Minimum inhibitory concentration (MIC) was assessed using serial dilution method.ResultsThe research results showed the presence of Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans, Prevotella intermedia, Streptococcus salivaris and Staphylococcus aureus in the subgingival samples from peri-implantitis patients. Statistically, significantly higher proportion of samples had Porphyromonas gingivalis. When subjected to the effect of L. reuteri, all the microorganisms were affected by L.reuteri except Aggregatibacter actinomycetemcomitans.ConclusionThis study provides the various MIC value for each isolated pathogen against L.reuteri. The authors recommend to avoid using standard guidelines for probiotic dose in the treatment of peri-implant infections as the antimicrobial profile is different for each periodontal pathogen.
Highlights
Probiotics affect both the development and stability of microbiota by altering the colonization of pathogens and helps in stimulating the immune system of the individual
Each patient sample was subjected to microbial testing to identify the peri-implantitis microorganisms
Five types of microorganisms were detected in 35 samples: Porphyromonas gingivalis (P.gingivalis), Aggregatibacter actinomycetemcomitans (A.a), Prevotella intermedia(P. intermedia), Streptococcus salivaris (Strep.salivaris), Staphylococcus aureus (Staph.aureus) (Table 1)
Summary
Probiotics affect both the development and stability of microbiota by altering the colonization of pathogens and helps in stimulating the immune system of the individual. The aim of the present study is to assess the effect of probiotics on peri-implantitis microflora, by determining the minimum inhibitory concentration (MIC) of Lactobacillus reuteri, that can be effectively administered as an antimicrobial agent on specific peri-implantitis pathogens. Reuteri that can be effectively administered as an antimicrobial agent on specific peri-implantitis pathogens. A cause-effect relationship has been identified between the accumulation of bacterial plaque and the development of inflammatory changes in the soft tissues surrounding oral implants. Procedures are aimed to prevent and treat any such peri-implantitis through different methods. These include mechanical debridement, surgical therapy with or without regenerative procedures, local or systemic antibiotics
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
