Abstract
Textile-based Scaffolds preparation has the attractive features to fulfill the stated and implied needs of the consumer but there are still challenges of stability, elongation, appreciable bio-compatibility, and stated hydrophilic behavior. To overcome these challenges, the authors tried to fabricate a scaffold by blending of two highly biocompatible polymers; polyvinyl alcohol and poly(1,4 cyclohexane isosorbide terephthalate) through co-electrospinning. The resultant scaffold by the stated innovative approach evaluated from different characterizations such as dimensional stability/morphology was evaluated by scanning electron microscopy, chemical interactions by that Fourier transmission infrared spectra, wetting behavior was analyzed by a static angle with a contact angle meter from drop method, elongation was examined by tensile strength tester and in-vitro assessment was done by MTT analysis. Based on verified results, it was concluded that PVA/PICT scaffold has a potential for dual nature of hydrophilicity & hydrophobicity and appreciable cell culture growth, stated dimensional stability and suitable elongation as per requirements of the nature of scaffold.
Highlights
Textile-based Scaffolds preparation has the attractive features to fulfill the stated and implied needs of the consumer but there are still challenges of stability, elongation, appreciable biocompatibility, and stated hydrophilic behavior
In case of hydrophilic surface, the contact angle between the surface and the water droplet is less than 90°, as a result when the water droplet falls in the surface of material it will be adsorbed on the surface of material instead of rolling off
From all the histograms it can be concluded that the PICT electrospun nanofibers with the highest values of standard deviation show more variation in the structure, while the PVA electrospun nanofibers have an excellent surface structure with a fine diameter as compare to PICT and blend (PVA: PICT) electrospun nanofibers but the blended form is better than neat PICT nanofibers
Summary
Textile-based Scaffolds preparation has the attractive features to fulfill the stated and implied needs of the consumer but there are still challenges of stability, elongation, appreciable biocompatibility, and stated hydrophilic behavior. Blend electrospun nanofibers show the peaks of C and O but in this case, the intensity of C and O peaks increased due to the mixing of PVA and PICT nanofibers.
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