Abstract

Plants and plants products are the major sources of natural antioxidant which can be used to ameliorate oxidative stress caused by reactive oxygen species in biological systems. In vitro antioxidant activity of Musa paradisiacapeel aqueous extract was evaluated. Sodium nitroprusside was used to induce lipid perioxidation in rat pancreas. The total phenol, flavonoid and vitamin C contents were determined using standard methods of analysis. OH radical scavenging ability, Fe2+ chelating ability and lipid peroxidation were also analyzed using standard methods. The result revealed substantial amount of total phenol (0.76 ±0.04 mg/g), total flavonoid (0.53 ±0.04 mg/g) and vitamin C contents (24.11 ±0.41 mg/100 g). The result also revealed increased OH radical scavenging ability, Fe2+ chelating ability and MDA inhibition with increase in concentration of the extract used. The present study therefore, revealed that Musa paradisiacapeel aqueous extract could serve as source of natural antioxidant which can be used to ameliorate some disease associated with oxidative stress.

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