Abstract

Antimicrobial activity of endophytic fungi from marine Sponge Haliclona fascigeraDian Handayani, Rizka Fauza Ahdinur, R. Rustini

Highlights

  • Endophytic fungi reside within most tissues of the living plants which are known to possess different rare and novel secondary metabolites (Ibrahim et al, 2015)

  • We investigated five fungal endophytes associated with the medicinal plant Mussaenda luteola L. (Rubiaceae) for the presence of phytochemicals, total phenolic, total flavonoid content, antioxidant and antibacterial activity

  • Isolation and identification of endophytic fungi The healthy leaf, stem and root of the plant M. luteola were subjected to isolate the endophytic fungi and the identification was based on colony morphology and microscopic studies

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Summary

Introduction

Endophytic fungi reside within most tissues of the living plants which are known to possess different rare and novel secondary metabolites (Ibrahim et al, 2015) It proved to be one of the most important and diverse resources available for active natural products with significant biological activities (Peng et al, 2013). There are large number of bioactive compounds that have been isolated and identified from endophytic fungi which has various biological activities such as antioxidant, anticancer, antiviral, immunomodulatory, antitubercular, insecticidal and antiparasitic activities These bioactive natural products have a wide application in pharmaceuticals and agrochemical industries (Hussain et al, 2014; Chomcheon et al, 2009). These free radicals cause oxidative stress leading to damage membrane

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