Abstract
Background: The Siddha system of medicine uses a interesting combination of herbs, minerals and metals to promote good health and longevity. Parangipattai Rasayanam is a polyherbal formulation mentioned in the Siddha literature and is indicated for Soolai (Pain), Viranam (Various ulcers), Kiranthi (Venereal diseases), Kuttam (Skin diseases), Gunmam (peptic ulcer) and Moorchai.
 Aim: Evaluate the in-vitro antioxidant activity of Parangipattai Rasayanam.
 Materials & Methods: The antioxidant activity of Parangipattai Rasayanam was evaluated by using various assays such as DPPH (2, 2-Diphenyl 1-2 picrylhydrazyl) Assay, Nitric Oxide Radical Scavenging Assay, ABTS Assay, Hydrogen Peroxide Radical Scavenging Assay.
 Result: Parangipattai Rasayanam has promising anti-oxidant activity in the estimated assays.
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