Abstract
Medicinal plants are the wealthy source of antibacterial agents and curatives. There is an urgent need for new antimicrobial agents, so the antimicrobial activity for Ruta graveolens L. and Ficus carica Linn. Crude extracts were evaluated for its inhibitory activity against some disease causing selected microorganisms. Root extract of Ruta graveolens L gave 8 and 7 mm inhibition zone against Escherichia coli 254607 and Pseudomonas aeruginosa 254992 respectively. Latex of Ficus carica Linn plants showed that it is a good inhibitor for Candida albicans 254625; whereas the rest of microorganisms (Escherichia coli 254607, Proteus mirabilis 257440, Microsporium canis, Staphylococcus aureus 254996, Klebsiella pneumoniae 254656 and Staphylococcus epidermidis 254997) gave almost a similar inhibition zone around 2-3 mm. The tested crude extract from Ruta graveolens L. and Ficus carica Linn. have proved to be promising treating agents against the tested pathogenic microbes, but it needs to be concentrated and furthermore evaluated.
Highlights
In recent times, there have been increases in antibiotic resistant strains of clinically important pathogens, which have led to the emergence of new bacterial strains that are multi-resistant (Davies & Davies, 2010)
The plant extracts were assayed against following microorganisms: Pseudomonas aeruginosa 254992, Candida albicans 254625, Proteus mirabilis 257440, Escherichia coli 254607, Microsporium canis, Staphylococcus aureus 254996, Klebsiella pneumoniae 254656 and Staphylococcus epidermidis 254997, which have been stored in "Blood Bank in Al-Baha)
The problem of microbial resistance some time takes the shape of epidemic due to development of drug resistant microorganisms in recent year lot of attention is diverted to discover new source of natural antimicrobial agents
Summary
There have been increases in antibiotic resistant strains of clinically important pathogens, which have led to the emergence of new bacterial strains that are multi-resistant (Davies & Davies, 2010). There is a need to look for substances from other sources with proven antimicrobial activity This has led to the search for more effective antimicrobial agents among materials of plant origin, with the aim of discovering potentially useful active ingredients that can serve as source and template for the synthesis of new antimicrobial drugs (Moreillion, Que, & Glauser, 2005). The crushed leaves as well as the extracted juice are mixed with shear butter or palm oil and rubbed on abscesses or other swellings. This is applied on ulcers, burns and on the bodies of young children when they are ill. The plant is rich in both macro and micro elements, vitamins, calcium,phosphorus, ascorbic acid, inulin (Okwu & Josiah, 2006) and other compounds like saponin, flavonoids, anthraquinones, xanthones, bryophyllin
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