Abstract

In vitro Antidiabetic Activity of Methanolic Leaf Extract of Indianthus virgatus (Roxb.) Suksathan and Borchs by Glucose Uptake Method

Highlights

  • Diabetes Mellitus is an established noncommunicable disease and often described as fourth or fifth leading cause of mortality in high income countries.[1]

  • Glucose uptake activity of test substance was determined in differentiated L-6 cells

  • The results of the current study clearly demonstrated the antidiabetic potency of methanolic leaf extract obtained from Indianthus virgatus (Roxb.) Suksathan and Borchs. under in vitro model

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Summary

Introduction

Diabetes Mellitus is an established noncommunicable disease and often described as fourth or fifth leading cause of mortality in high income countries.[1]. Some of the standard synthetic drugs used for the treatment of diabetes are sulfonylureas, biguanides, α-glucosidase inhibitors, glinides, etc These drugs tend to cause side effects like nausea, vomiting, abdominal pain, diarrhea, head ache, abnormal weight gain, allergic reaction, low blood glucose, dark urine, fluid retention, or swelling. They are not safe for use during pregnancy.[3] the management of diabetes without any side effects is still a challenge. Active research has been performed on traditionally available medicinal plants for the discovery of new antidiabetic drug as an alternative.[8]

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