Abstract
Herbal medicines gained an interest in the development of new drugs as a therapeutic agent for various manifestation. Relevant research reveals that Thunbergia coccinea is a plant which possess antipyretic, anti-inflammatory activity and it has been used as an ethnomedicinal plant. The present study explores the cholinesterase inhibitory potential relevant to neurodegenerative disorder and antioxidant activities of hydroethanolic extract of Thunbergia coccinea leaves. Cholinesterase inhibition was determined by Ellman method at different concentrations. The antioxidant activity was assessed by DPPH, FRAP, ABTS, TRAP, NO radical inhibition assay, Phosphomolybdate assay for total antioxidant capacity, total phenolic content, SOD scavenging activity. The hydroethanolic extract of Thunbergia coccinea leaves express significant amount of antioxidant and anticholinesterase activity against neurodegenerative disorders.
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