Abstract
Objective: The present study was carried out to assess the in vitro anthelmintic activity of Abutilon theophrasti stem extracts.
 Methods: Simple maceration was employed for extraction. Solvents such as methanol, water, and hexane were used. Egg hatch test (EHT) and larval motility test were employed to check the anthelmintic activity of crude extracts. Concentrations of 500, 250, 125, 62.5, and 31.25 mg/ml were made. Levamisole and distilled water served as control, respectively.
 Results: All selected extracts displayed concentration-dependent inhibition except aqueous extracts. At higher concentration (500 mg/ml), stem extracts (methanol, aqueous, and ethanol) showed 74.39%, 72.5 and 70.03% of efficacy in EHT, respectively (p≤0.05). Meanwhile, inhibition of larval motility was seen higher with inhibition percentage of 79.79, 75.65, and 71.28 by methanolic, aqueous, and hexane extracts, respectively (p≤ 0.05).
 Conclusion: The presents study suggests active principles having anthelmintic efficacy in Abutilon theopharsti stem.
Highlights
Helminthiasis is one of the most important animal diseases worldwide, inflicting heavy production losses on grazing animals
An integrated approach is required for the effective control of the helminths and careful management of grazing lands including control of stocking rates and appropriate rotation strategies; problems have emerged with the use of anthelmintics, and development of resistance in helminths is a problem of major concern
Our present study was done with the same aspiration to assess the anthelmintic activity of Abutilon theophrasti
Summary
Solvents such as methanol, water, and hexane were used. Egg hatch test (EHT) and larval motility test were employed to check the anthelmintic activity of crude extracts. Concentrations of 500, 250, 125, 62.5, and 31.25 mg/ml were made. Levamisole and distilled water served as control, respectively
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