Abstract
This article includes datasets acquired by Raman spectroscopy from in vivo and in vitro ocular samples collected from the dataset from Bertens and Zhang et al., “Confocal Raman spectroscopy: Evaluation of a non-invasive technique for the detection of topically applied ketorolac tromethamine in vitro and in vivo” (Bertens and Zhang, et al.). Detection of ketorolac tromethamine in pig eyes was performed in vitro and rabbit eyes in vivo. Extracted aqueous humor samples from pig and rabbit eyes were measured in vitro using a cuvette. This manuscript shows the spectral Raman data without pre-treatment or analysis from ocular tissues and provides further information towards aqueous humor research via alternative data processing methods. Furthermore, the raw data enclosed may be used for future aqueous humor investigations and pharmaceutical research.
Highlights
In vitro and in vivo datasets of topically applied ketorolac tromethamine in aqueous humor using Raman spectroscopy
This article includes datasets acquired by Raman spectroscopy from in vivo and in vitro ocular samples collected from the dataset from Bertens and Zhang et al, “Confocal Raman spectroscopy: Evaluation of a non-invasive technique for the detection of topically applied ketorolac tromethamine in vitro and in vivo” (Bertens and Zhang, et al.)
The dataset can be useful for researchers who are interested in the aqueous humor composition, ocular pharmaceutics, Raman spectroscopy, and software engineers
Summary
The dataset can be useful for researchers who are interested in the aqueous humor composition, ocular pharmaceutics, Raman spectroscopy, and software engineers. Alternative processing methods could be applied to exact other compounds in the aqueous humor or to enhance signals This dataset offers a large cohort of animals measured on both eyes, 5 times. Several peaks could be identified in the fingerprint region spectrum of a ketorolac tromethamine sample (Fig. 1a). Major peaks specific for ketorolac tromethamine were selected Those peaks are assigned to certain chemical bonds or vibration modes. Because Raman spectrum of the cornea, aqueous humor, and lens show different patterns in the high-wavenumber region, spectra from this region could be used as guide for location determination in the ocular tissue (Fig. 1b) [4e6]. The location in the eye was determined using the high-wavenumber spectra (Fig. 2b)
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
