Abstract

Generation of mouse models for COVID-19 pathogenesis is of keen interest as they would allow for efficient investigation of disease mechanisms, as well as providing a vaccine and drug development platform. However, the current transgenic hACE2 ...The classical manifestation of COVID-19 is pulmonary infection. After host cell entry via human angiotensin–converting enzyme II (hACE2), the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus can infect pulmonary epithelial cells, ...

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