In straw dilution of bovine IVF-blastocysts cryopreserved by vitrification

Abstract

Drug targeting facilitates the drug to reach its appropriate site so as to show the desired pharmacological response as per the therapeutic need. A clear understanding of the level of targeting makes it easy to decide the suitable targeting moiety, ligand, or carrier system. Also, targeted delivery allows a minimum amount of drug reaching the nontarget organs and tissues to provide an efficacious and safe drug delivery system. Broadly there may be three drug targeting levels: first, second, and third, assigned to organs, cells, and organelles respectively. A fourth level is assigned to the molecular level of targeting. The chapter discusses the different approaches of targeting including passive, inverse, active, physical, dual and ligand-mediated targeting along with different factors affecting targeting. This chapter also expounds the therapeutic examples of drug targeting to a sufficient length.