Abstract

Distinct evolution of Au nanostructures was noted spectrophotometrically at localized surface plasmon resonance band centre at around 580nm in a reaction mixture of uric acid and gold chloride solution at room temperature. In-situ formation of Au nanostructures during oxidation of uric acid was confirmed via transmission electron microscopy, energy dispersive X-ray, ultraviolet-visible spectroscopy and X-ray diffraction analyses. The ensuing Au particles exhibit brick red colour appearance and were not monodispersed. They dominantly constitute nearly spherical as well as rod like elongated structures to about 1000nm in length. Nanozyme behaviour of the produced Au particles was not observed. This formation of Au nanostructures during the oxidation reaction might intuitively illustrate traditionally practice chrysotherapy mechanism of hyperuricemia.

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