Abstract
The Laser-Induced Breakdown Detection technique (LIBD) was adapted to achieve fast in-situ characterization of nanoparticle beams focused under vacuum by an aerodynamic lens. The method employs a tightly focused, 21 μm, scanning laser microprobe which generates a local plasma induced by the laser interaction with a single particle. A counting mode optical detection allows the achievement of 2D mappings of the nanoparticle beams with a reduced analysis time thanks to the use of a high repetition rate infrared pulsed laser. As an example, the results obtained with Tryptophan nanoparticles are presented and the advantages of this method over existing ones are discussed.
Highlights
An experimental setup, including a scanning laser microprobe, has been developed to perform a direct characterization of the aerodynamic lens focusing via a 2D mapping of the nanoparticle beam produced by an ALS
We present here a technique derived from LIBD for in-situ probing of nanoparticle beams under vacuum
Beam profile measurements were performed on Tryptophan (C11H12N2O2) nanoparticles, a molecule commonly used in the framework of biomolecular studies on PLEIADES beamline at the Synchrotron SOLEIL facility
Summary
An experimental setup, including a scanning laser microprobe, has been developed to perform a direct characterization of the aerodynamic lens focusing via a 2D mapping of the nanoparticle beam produced by an ALS. The laser focusing system is designed to allow single particle detection, and the use of a high repetition rate pulsed laser (up to 25 kHz), never tested for LIBD measurements, permits fast nanoparticles sampling.
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