Abstract
The photoconductive antenna microprobe-based terahertz (THz) near-field scanning microscope has proven to overcome the diffraction limit and demonstrated the potential in distinguishing cellular types and states. Here, using the onion epidermal cells as a sample model, detection of single epithelial cell in the onion skin has been realized at amplitude signal around 1 THz. The boundaries of the target cells in a monolayer onion epidermis are clearly depicted with the spatial resolution of 9 <italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">μ</i> m (λ/33). Differentiated THz dielectric response shows clearly the distinctive intracellular and intercellular regions, mainly related to the biowater distribution and cellular heterogeneity, which can be used for <italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">in situ</i> subcellular identification <italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">.</i> This finding may have significant implications for the advancement of THz near-field high-resolution bioimaging technology.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: IEEE Transactions on Terahertz Science and Technology
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
