Abstract
a peer-reviewed, open access online international journal which publishes original research papers. The journal welcomes submission from scholars and experts for possible publication from all over the world. The scope of the journal includes: Pharmaceutical research, chemistry and biochemistry of naturally occurring compounds, biological evaluation of crude extracts, ethnomedicine, traditional and complementary medicine, ethnopharmacology, biomedical research, Biotechnology, Evaluation of natural substances of land and sea and of plants, microbes and animals, pharmacognosy, bioavailability, clinical, pharmacological, toxicological studies and pharmacokinetics of phytochemicals, Isolation and characterization of compounds, structure elucidation, synthesis and experimental biosynthesis of natural Product as well as developments of methods in these areas are welcomed in the journal.
Highlights
The plant Ocimum gratissimum L. is a culinary herb of the Labiatae family, and is native to India and West Africa, where it is called African Basil.[1,2] It is found in the Savannah and coastal areas in Nigeria where it is called “Nchanwu” by the Igbos, “efinrin-nla” by the Yorubas, and “Dadoya” by the Hausas.[3,4] The presence of essential oil in the leaves of O. gratissimum impacts the plant with a unique fragrance.[5,6] Characterization of this essential oil has shown the presence of phytochemicals like eugenol, thymol, geraniol, βcaryophyllene, valencene, p-cymene, etc.[7]
The compounds identified in the gas chromatograph (GC)-flame ionization detector (FID) analysis and their concentrations are shown in Figure 2 and Table 1, respectively
In the docking studies of components from the essential oil of Trachyaspermum ammi a g a i ns t Candidapepsin-1 enzyme, it was observed that the compound ligustillide had the highest binding affinity (–5.8 Kcal/mol) on the most extensive active site of this enzyme.[23]
Summary
The plant Ocimum gratissimum L. is a culinary herb of the Labiatae family, and is native to India and West Africa, where it is called African Basil.[1,2] It is found in the Savannah and coastal areas in Nigeria where it is called “Nchanwu” by the Igbos, “efinrin-nla” by the Yorubas, and “Dadoya” by the Hausas.[3,4] The presence of essential oil in the leaves of O. gratissimum impacts the plant with a unique fragrance.[5,6] Characterization of this essential oil has shown the presence of phytochemicals like eugenol, thymol, geraniol, βcaryophyllene, valencene, p-cymene, etc.[7] In traditional medicine, the crude extract from the leaf of this plant has been used to treat different ailments and diseases like high fever, cold, fungal infection, epilepsy, and diarrhea.[8] The essential oil has been reported to have pronounced antimicrobial activity against different bacteria and fungi.[9] It has been incorporated in various bases as topical antiseptics in treating minor wounds, boils, and pimples.[10]
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