Abstract
Parkinsonism, one of the most frequent CNS disorders characterized by tremor and hypokinesia. Several people affected from this disorder due to concurrent use of medications results as side effect. In this computational research investigation, we performed In-silico pharmacokinetic, bioactivity and toxicity study of some selected anti-parkinsonism agents. To design a new molecule having good pharmacological profile, this study will provide the lead information.Key Words: QSAR, TPSA, In Silico, bioactivity, Log P
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