Abstract
A range of cytokines are altered during sepsis. Multiplex analysis of inflammatory mediators makes it easier to study a larger range of mediators, and combined with newer bioinformatical tools (unsupervised hierarchical clustering), this has the potential to bring new knowledge of the inflammatory process during sepsis.
Highlights
A range of cytokines are altered during sepsis
88% of bacteraemia patients are discriminated by unsupervised hierarchical cluster analysis of 5 inflammatory mediators
Multiplex analysis of inflammatory mediators makes it easier to study a larger range of mediators, and combined with newer bioinformatical tools, this has the potential to bring new knowledge of the inflammatory process during sepsis
Summary
To investigate if there are differences in expression of multiple inflammatory mediators between septic patients with and without bacteraemia during the initial phase of hospitalization, in order to identify bacteraemic patients
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