Abstract

To the Editor: We appreciate the comments from Drs. Cengiz, Özyar, and Atahan. They examined their patients based on our classification of NPC patients into low-, intermediate-, and high-risk groups ( 1 Cheng S.H. Yen K.L. Jian J.M. et al. Examining prognostic factors and patterns of failure in nasopharyngeal carcinoma following concomitant radiotherapy and chemotherapy Impact on future clinical trials. Int J Radiat Oncol Biol Phys. 2001; 50: 717-726 Abstract Full Text Full Text PDF PubMed Scopus (86) Google Scholar ). Unfortunately, they were unable to reproduce our observations. What are the potential reasons? Cengiz et al. did not mention the imaging tool used for the head-and neck-evaluation or the technique of radiotherapy use in their patients. We assume they evaluated the head-and neck-tumors mainly by CT and treated their patients using conventional radiotherapy rather than CT-assisted radiotherapy ( 2 Ozyar E. Yildiz F. Akyol F.H. et al. American Joint Committee on CancerComparison of AJCC 1988 and 1997 classifications for nasopharyngeal carcinoma. Int J Radiat Oncol Biol Phys. 1999; 44: 1079-1087 Abstract Full Text Full Text PDF PubMed Scopus (51) Google Scholar ).

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