Abstract

To the Editor: We would like to thank Drs. Wei and Mei from the Department of Radiation Oncology, Xijing Hospital, for their interest in our manuscript ( 1 Georg P. Lang S. Dimopoulos J.C.A. et al. Dose-volume histogram parameters and late side effects in magnetic resonance-image guided cervical cancer adaptive radiotherapy. Int J Radiat Oncol Biol Phys. 2011; 79: 356-362 Abstract Full Text Full Text PDF PubMed Scopus (156) Google Scholar ). To clarify our dose–volume assessment and outcome, we would like to emphasize the following with respect to the questions in their letter to the editor ( 2 Mei S, Wei L. Dose-volume histogram parameters and later side effects in magnetic resonance image-guided adaptive cervical cancer brachytherapy. In regard to Georg P, Lang S, Dimopoulos JCA, et al. (Int J Radiat Oncol Biol Phys 2011;79:356–362). Int J Radiat Oncol Biol Phys 2011, in press. Google Scholar ). Dose–Volume Histogram Parameters and Late Side Effects in Magnetic Resonance Image–Guided Adaptive Cervical Cancer Brachytherapy: In Regard to Georg et al. (Int J Radiat Oncol Biol Phys 2011;79:356–362)International Journal of Radiation Oncology, Biology, PhysicsVol. 81Issue 1PreviewTo the Editor: We read the paper wrote by Georg (1) and very interested in their work (1–3). Their data and experience are valuable for promoting the usage of image-guided brachytherapy and improving the treatment outcome of cervical cancer. We found that the mean D2cc for rectum were 65 Gy for all patients in their study, which were a little lower than the standard dose constrain recommended by GEC-ESTRO (cutoff dose is 75 Gy). Our data (4), similar to Koom’s report (5), showed that 74.97 ± 1.64 Gy of mean D2cc-rectum led to 50% Grade 1-2 rectal complication without severe toxicity. Full-Text PDF

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