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Academic Emergency MedicineVolume 13, Issue 9 p. 999-1000 Free Access In reply H. Bryant Nguyen MD, MS, H. Bryant Nguyen MD, MS (hbnguyen@ahs.llumc.edu)Search for more papers by this authorStephen W. Corbett MD, PhD, Stephen W. Corbett MD, PhD Loma Linda University Medical Center, Loma Linda, CASearch for more papers by this author H. Bryant Nguyen MD, MS, H. Bryant Nguyen MD, MS (hbnguyen@ahs.llumc.edu)Search for more papers by this authorStephen W. Corbett MD, PhD, Stephen W. Corbett MD, PhD Loma Linda University Medical Center, Loma Linda, CASearch for more papers by this author First published: 28 June 2008 https://doi.org/10.1197/j.aem.2006.05.002AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat No abstract is available for this article. References Nguyen HB, Corbett SW Menes K, et al. Early goal-directed therapy, corticosteroid, and recombinant human activated protein C for the treatment of severe sepsis and septic shock in the emergency department. Acad Emerg Med. 2006; 13: 109– 13. Loma Linda University Medical Center. The STOP Sepsis Bundle Toolkit. Available at: http:www.llu.edullumcemergencypatientcare20042006. Accessed June 12, 2006. Institute for Healthcare Improvement. Sepsis Bundle: Surviving Sepsis Campaign and Institute for Healthcare Improvement. Available at: http:www.ihi.orgIHITopicsCriticalCareSepsis2005. Accessed June 12, 2006. Rivers E, Nguyen B Havstad S, et al. Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med. 2001; 345: 1368– 77. Annane D, Sebille V Charpentier C, et al. Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock. JAMA. 2002; 288: 862– 71. Bernard GR, Vincent JL Laterre PF, et al. Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med. 2001; 344: 699– 709. Abraham E, Laterre PF Garg R, et al. Drotrecogin alfa (activated) for adults with severe sepsis and a low risk of death. N Engl J Med. 2005; 353: 1332– 41. Ely EW, Laterre PF Angus DC, et al. Drotrecogin alfa (activated) administration across clinically important subgroups of patients with severe sepsis. Crit Care Med. 2003; 31: 12– 9. Angus DC, Laterre PF Helterbrand J, et al. The effect of drotrecogin alfa (activated) on long-term survival after severe sepsis. Crit Care Med. 2004; 32: 2199– 206. Angus DC, Linde-Zwirble WT Clermont G, et al. Cost-effectiveness of drotrecogin alfa (activated) in the treatment of severe sepsis. Crit Care Med. 2003; 31: 1– 11. Manns BJ, Lee H, Doig CJ, Johnson D, Donaldson C. An economic evaluation of activated protein C treatment for severe sepsis. N Engl J Med. 2002; 347: 993– 1000. Huang DT, Angus DC, Dremsizov TT, Rivers EP, Clermont G. Cost-effectiveness of early goal-directed therapy in the treatment of severe sepsis and septic shock. Crit Care. 2003; 7: S116. Wolff AM, Taylor SA McCabe JF. Using checklists and reminders in clinical pathways to improve hospital inpatient care. Med J Aust. 2004; 181: 428– 31. Abella BS, Rhee JW, Huang KN, Vanden Hoek TL, Becker LB. Induced hypothermia is underused after resuscitation from cardiac arrest: a current practice survey. Resuscitation. 2005; 64: 181– 6. Majumdar SR, Simpson SH Marrie TJ. Physician-perceived barriers to adopting a critical pathway for community-acquired pneumonia. Jt Comm J Qual Saf. 2004; 30: 387– 95. Rello J, Lorente C, Bodi M, Diaz E, Ricart M, Kollef MH. Why do physicians not follow evidence-based guidelines for preventing ventilator-associated pneumonia?: a survey based on the opinions of an international panel of intensivists. Chest. 2002; 122: 656– 61. Jones AE. Evidence-based therapies for sepsis care in the emergency department: striking a balance between feasibility and necessity. Acad Emerg Med. 2006; 13: 82– 3. Volume13, Issue9September 2006Pages 999-1000 ReferencesRelatedInformation