Abstract

To the Editor: I read with great interest the article by Baumann et al ( 1 Baumann B.C. Bosch W.R. Bhal A. et al. Development and validation of consensus guidelines for adjuvant radiation therapy for bladder cancer after cystectomy. Int J Radiat Oncol Biol Phys. 2016; 96: 78-86 Abstract Full Text Full Text PDF Scopus (35) Google Scholar ) on consensus guidelines for adjuvant radiation therapy for bladder cancer. The authors state these guidelines have been adopted by the NRG-GU001 phase 2 trial of postoperative adjuvant IMRT following cystectomy for pT3/pT4 urothelial bladder cancer ( 2 NRG Oncology. NRG-GU001: Randomized phase II trial of postoperative adjuvant IMRT following cystectomy for pT3/pT4 urothelial bladder cancer. Version date: January 2, 2015. Available at: https://www.nrgoncology.org/Clinical-Trials/NRG-GU001. Accessed June 16, 2016. Google Scholar ). Development and Validation of Consensus Contouring Guidelines for Adjuvant Radiation Therapy for Bladder Cancer After Radical CystectomyInternational Journal of Radiation Oncology, Biology, PhysicsVol. 96Issue 1PreviewTo develop multi-institutional consensus clinical target volumes (CTVs) and organs at risk (OARs) for male and female bladder cancer patients undergoing adjuvant radiation therapy (RT) in clinical trials. Full-Text PDF In Reply to LeungInternational Journal of Radiation Oncology, Biology, PhysicsVol. 96Issue 5PreviewTo the Editor: We thank Dr Leung for the opportunity to clarify apparent discrepancies between the international consensus contouring guidelines in our article (1) and NRG GU001, a randomized phase 2 trial of postoperative adjuvant IMRT following cystectomy for pT3/pT4 urothelial bladder cancer. The initial draft of NRG GU001 was completed before the international consensus recommendation was completed. With its most recent amendment (version date June 13, 2016), NRG GU001 is now consistent with the consensus guidelines and requires that the nodal clinical target volume be cropped off of muscle and bone and should commence superiorly at the L5-S1 interface. Full-Text PDF

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